Factors associated with mortality in children receiving antiretroviral therapy
| Crude | Adjusted | ||||
|---|---|---|---|---|---|
| No. | HR (95% CI) | p Value | aHR (95% CI) | p Value | |
| Sex | |||||
| Female | 227 | 1.00 | 1.00 | ||
| Male | 250 | 0.88 (0.44 to 1.77) | 0.726 | 0.64 (0.29 to 1.42) | 0.296 |
| Weight-for-age | |||||
| >−1 | 116 | 1.00 | 1.00 | ||
| >−2 to −1 | 115 | 6.14 (0.74 to 50.99) | 0.093 | 3.88 (0.45 to 33.62) | 0.218 |
| ≤−2 | 178 | 12.52 (1.67 to 93.80) | 0.014 | 5.95 (0.74 to 47.45) | 0.092 |
| Missing | 68 | 12.68 (1.56 to 103.04) | 0.018 | 3.95 (0.42 to 37.20) | 0.230 |
| CD4 cell per cent | |||||
| ≤20 | 134 | 1.00 | 1.00 | ||
| 10 to <20 | 104 | 1.46 (0.29 to 7.25) | 0.643 | 1.17 (0.23 to 5.94) | 0.852 |
| <10 | 61 | 5.07 (1.27 to 20.33) | 0.022 | 3.61 (0.87 to 14.97) | 0.076 |
| Missing | 178 | 5.75 (1.71 to 19.38) | 0.005 | 3.52 (0.97 to 12.69) | 0.054 |
| Haemoglobin | |||||
| ≥8 | 341 | 1.00 | 1.00 | ||
| <8 | 31 | 6.53 (2.82 to 15.15) | <0.001 | 4.49 (1.63 to 12.33) | 0.004 |
| Missing | 105 | 1.45 (0.59 to 3.49) | 0.413 | 1.12 (0.37 to 3.38) | 0.834 |
| Albumin | |||||
| >27 | 232 | 1.00 | 1.00 | ||
| ≤27 | 145 | 3.63 (1.63 to 8.09) | 0.002 | 1.89 (0.79 to 4.51) | 0.147 |
| Missing | 100 | 1.41 (0.47 to 4.21) | 0.538 | 0.71 (0.18 to 2.80) | 0.628 |
| WHO staging | |||||
| 1 and 2 | 97 | 1.00 | 1.00 | ||
| 3 and 4 | 317 | 4.07 (0.96 to 17.25) | 0.057 | 3.31 (0.67 to 16.18) | 0.139 |
| Missing | 63 | 5.47 (1.10 to 27.12) | 0.037 | 5.49 (0.92 to 32.76) | 0.062 |
| TB initiation | |||||
| No | 343 | 1.00 | 1.00 | ||
| Yes | 105 | 0.65 (0.25 to 1.70) | 0.384 | 0.60 (0.22 to 1.64) | 0.323 |
| Missing | 29 | 0.43 (0.06 to 3.17) | 0.408 | 0.61 (0.07 to 5.07) | 0.646 |
| Age group | |||||
| ≥60 months | 287 | 1.00 | 1.00 | ||
| <18 months | 58 | 0.51 (0.18 to 1.47) | 0.213 | 3.24 (1.15 to 9.12) | 0.026 |
| 18–59 months | 132 | 0.49 (0.19 to 1.25) | 0.141 | 0.93 (0.38 to 2.28) | 0.869 |
HR, hazard ratio; aHR, adjusted hazard ratio.