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Are topical corticosteroids superior to systemic histamine antagonists in treatment of allergic seasonal rhinitis?
  1. Charles C Roehr1,
  2. Johannes Forster2
  1. 1SHO in Paediatrics, John Radcliffe Hospital, Oxford, UK
  2. 2Professor of Paediatrics, St Josefskrankenhaus Pädiatrie (St Hedwig), Freiburg, Germany

https://doi.org/10.1136/adc.87.5.412

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    You receive a call from one of your adolescent patients, a 16 year old boy with a longstanding history of seasonal allergic rhinitis (SAR). He is currently treating his mainly nasal symptoms with an oral histamine antagonist (OH1A). His symptoms are getting increasingly difficult to control. He is worried about the upcoming hay fever season and asks for other treatment options.

    Structured clinical question

    In a 16 year old [patient] are topical corticosteroids [intervention] more effective than oral histamine antagonists [comparison intervention] in the alleviation of symptoms of seasonal allergic rhinitis [outcome]?

    Search strategy and outcome

    Search engine—PubMed: “allergic rhinitis and adrenal-cortex-hormones and meta-analysis” (MeSH-Terms).

    Search results—two articles found, one original meta-analysis.

    Secondary sources—Consensus Statement, European Academy of Allergology and Clinical Immunology.

    See table 1.

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    Table 1

    Topical corticosteroids v systemic histamine antagonists in treatment of allergic seasonal rhinitis

    Commentary

    The meta-analysis by Weiner et al …

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    Footnotes

    • Bob Phillips