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The meningococcus tamed?

Abstract

Serogroup B Neisseria meningitidis is a frequent cause of invasive meningococcal disease, yet there are no effective vaccines suitable for routine immunisation. Limited efficacy has been shown with meningococcal outer membrane vacccines in children 4 years and older. Here we review the status of current research and consider new approaches to development of meningococcal serogroup B vaccines.

  • meningococcus
  • vaccine
  • meningitis
  • review
  • immunisation
  • Hib, Haemophilus influenzae type b
  • LPS, lipopolysaccharide
  • OMP, outer membrane protein
  • OMV, outer membrane vesicle

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