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Archives of Disease in Childhood 2006;91:2-5; doi:10.1136/adc.2005.075846
Copyright © 2006 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health

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PERSPECTIVE

Autism

Two new theories of autism: hyper-systemising and assortative mating

S Baron-Cohen

Correspondence to:
Correspondence to:
Prof. S Baron-Cohen
Autism Research Centre, Department of Psychiatry, University of Cambridge, Douglas House, 18b Trumpington Road, Cambridge CB2 2AH, UK; sb205@cam.ac.uk


Commentary on the papers by Williams et al (see page 8) and Harrison et al (see page 16)

Keywords: autism; assortative mating

The first 150 words of the full text of this article appear below.

The autistic spectrum comprises four subgroups: Asperger’s syndrome (AS),1,2 and high, medium, and low functioning autism.3 They all share the phenotype of social difficulties and obsessional interests.4 In AS, the individual has normal or above average IQ and no language delay. In the three autism subgroups there is invariably some degree of language delay, and the level of functioning is indexed by overall IQ.* These four subgroups are known as autism spectrum conditions (ASC).

Williams and colleagues5 searched electronic databases and bibliographies to carry out a meta-analysis of 42 studies of prevalence of autism spectrum conditions (ASC). From this, their most generous estimate was 20 per 10 000, or 0.2%. Harrison and colleagues6 used the "capture–recapture" technique in Lothian, Scotland, and their prevalence estimate was 44.2 per 10 000, or 0.44%. This corresponds to 1 child in 225. These estimates are clearly much higher than was the case in . . . [Full text of this article]


Relevant Articles

Prevalence of autistic spectrum disorders in Lothian, Scotland: an estimate using the "capture–recapture" technique
M J Harrison, A E O’Hare, H Campbell, A Adamson, and J McNeillage
Arch. Dis. Child. 2006 91: 16-19. [Abstract] [Full Text] [PDF]

Systematic review of prevalence studies of autism spectrum disorders
J G Williams, J P T Higgins, and C E G Brayne
Arch. Dis. Child. 2006 91: 8-15. [Abstract] [Full Text] [PDF]



This article has been cited by other articles:


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About 1% of children in the South Thames region have an autistic spectrum disorder
Evid. Based Ment. Health, February 1, 2007; 10(1): 28 - 28.
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J M Howard and S Baron-Cohen
This could be due to maternal testosterone... * Author's reply
Arch. Dis. Child., July 1, 2006; 91(7): 622 - 622.
[Full Text] [PDF]

eLetters:

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This could be due to maternal testosterone...
James M. Howard
ADC Online, 31 Jan 2006 [Full text]
Autism could be due to maternal testosterone...
Simon Baron-Cohen
ADC Online, 1 Feb 2006 [Full text]



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