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Cardiac disease and Rett syndrome

¹ Section of Internal Medicine, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy
² Section of Clinical Immunology, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy

Correspondence to:
Correspondence to:
Dr M Acampa
Dipartimento di Medicina Clinica e Scienze Immunologiche, Sezione di Medicina Interna, Policlinico ‘Le Scotte’, viale Bracci, 53100 Siena, Italy; M.Acampa{at}ao-siena.toscana.it

ABSTRACT
Rett syndrome (RS) is a neurodevelopmental disease,1 affecting approximately 1 in 10 000–15 000 females.2 Clinical severity of RS may vary with increasing age, following a four stage model.3

Abbreviations: HRV, heart rate variability; RS, Rett syndrome; SD, sudden death

Keywords: QT interval prolongation; Rett syndrome; cardiac arrhythmias; heart rate variability; sudden death