ADC

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER


[Advanced]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this link to a friend
Right arrow Similar articles in ADC Online
Right arrow Similar articles in PubMed
Right arrow Add article to my folders
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lewindon, P J
Right arrow Articles by Lewindon, N
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lewindon, P J
Right arrow Articles by Lewindon, N
Arch Dis Child 1998;78:453-456 ( May )

Randomised controlled trial of sucrose by mouth for the relief of infant crying after immunisation

P J Lewindon,a L Harkness,a N Lewindonb

a Women's and Children's Hospital, Adelaide, South Australia, b Wakefield Street, Adelaide, South Australia

Correspondence to: Dr Peter Lewindon, Royal Children's Hospital, Brisbane, Herston, Queensland 4029, Australia.


Accepted 1 December 1997

OBJECTIVES---To evaluate the effect of sucrose solution given by mouth on infant crying times and measures of distress in the immunisation clinic.
DESIGN---Randomised, double blind, placebo controlled trial of sucrose solution 75% wt/vol v sterile water as a control.
SETTING---The immunisation clinic of the Women's and Children's Hospital, Adelaide.
PATIENTS---A total of 107 healthy infants attending for 2, 4, or 6 month immunisations with polio by mouth (Sabin), intramuscular diphtheria, tetanus, and pertussis (DTP), and intramuscular Haemophilus influenzae type b were randomised to receive 2 ml 75% sucrose solution or sterile water by mouth before the two injections.
METHODS---The duration of infant crying was recorded during and immediately after two intramuscular immunisations and infant distress was assessed by a visual analogue scale (Oucher scores) independently by a nurse and a parent.
RESULTS---The administration of 2 ml 75% sucrose solution by mouth reduced the infant crying time and Oucher distress scores after immunisation with DTP/H influenzae type b.
CONCLUSIONS---Infant immunisation by intramuscular injection is a distressing procedure for infants and parents. Sucrose solution at a high concentration reduces infant distress and is safe and clinically useful in this setting.

Keywords: infant analgesia; sucrose; immunisation

© 1998 by Archives of Disease in Childhood


This article has been cited by other articles:


Home page
 CMAJHome page
A. Taddio BScPhm PhD, V. Shah MD MSc, R. Hancock MSc, R. W. Smith BASc MSc, D. Stephens MSc, E. Atenafu MSc, J. Beyene PhD, G. Koren MD, B. Stevens RN PhD, and J. Katz PhD
Effectiveness of sucrose analgesia in newborns undergoing painful medical procedures
Can. Med. Assoc. J., July 1, 2008; 179(1): 37 - 43.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
L. A. Hatfield, M. E. Gusic, R. C. Polomano, and C. M. Berlin
Analgesic Properties of Oral Sucrose During Routine Immunizations: In Reply
Pediatrics, June 1, 2008; 121(6): 1295 - 1295.
[Full Text] [PDF]

Home page
 PediatricsHome page
D. Dilli
Analgesic Properties of Oral Sucrose During Routine Immunizations
Pediatrics, June 1, 2008; 121(6): 1294 - 1295.
[Full Text] [PDF]

Home page
 PediatricsHome page
L. A. Hatfield, M. E. Gusic, A.-M. Dyer, and R. C. Polomano
Analgesic Properties of Oral Sucrose During Routine Immunizations at 2 and 4 Months of Age
Pediatrics, February 1, 2008; 121(2): e327 - e334.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
N. L. Schechter, W. T. Zempsky, L. L. Cohen, P. J. McGrath, C. M. McMurtry, and N. S. Bright
Pain Reduction During Pediatric Immunizations: Evidence-Based Review and Recommendations
Pediatrics, May 1, 2007; 119(5): e1184 - e1198.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
E. Kozer, E. Rosenbloom, D. Goldman, G. Lavy, N. Rosenfeld, and M. Goldman
Pain in Infants Who Are Younger Than 2 Months During Suprapubic Aspiration and Transurethral Bladder Catheterization: A Randomized, Controlled Study
Pediatrics, July 1, 2006; 118(1): e51 - e56.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
W. T. Zempsky, J. P. Cravero, and Committee on Pediatric Emergency Medicine, and Sec
Relief of Pain and Anxiety in Pediatric Patients in Emergency Medical Systems
Pediatrics, November 1, 2004; 114(5): 1348 - 1356.
[Abstract] [Full Text] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
B. T. Felt, E. Mollen, S. Diaz, E. Renaud, M. Zeglis, G. Wheatcroft, and D. Mendelow
Behavioral Interventions Reduce Infant Distress at Immunization
Arch Pediatr Adolesc Med, July 1, 2000; 154(7): 719 - 724.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child.Home page
I. ABU-ARAFEH, M. CALLAGHAN, A. HILL, and S. HISLOP
Randomised controlled trial of sucrose by mouth for the relief of infant crying after immunisation
Arch. Dis. Child., November 1, 1998; 79(5): 465c - 465.
[Full Text]

Home page
 Arch. Dis. Child.Home page
I. CHOONARA and J. E BEYER
Randomised controlled trial of sucrose by mouth for the relief of infant crying by immunisation
Arch. Dis. Child., November 1, 1998; 79(5): 465d - 465.
[Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER
ARCH DIS CHILD FETAL NEONATAL ED ED PRACTICE
Terms and conditions relating to subscriptions purchased online  ¦  Website terms and conditions  ¦  Privacy policy
Copyright © 1998 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health