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Arch Dis Child 1997;76:362-364 ( April )

Basal ganglia infarction associated with HHV-6 infection

David W Webb,a Bruce H Bjornson,a Michael A Sargent,b Juliette Hukin,a Eva E Thomasc

a British Columbia's Children's Hospital, Vancouver, BC, Canada: Department of Paediatric Neurology, b Department of Radiology, c Department of Pathology and Laboratory Medicine

Correspondence to: Dr D W Webb, Royal Belfast Hospital for Sick Children, Falls Road, Belfast BT12 6BE.

Accepted 19 November 1996

A 6 year old boy presented with meningoencephalitis and was found to have serological evidence of acute human herpes virus-6 (HHV-6) infection. He did not develop symptomatic seizures or the rash of exanthum subitum (roseola). His course was marked by severe spastic quadriparesis associated with radiological evidence of basal ganglia infarction. HHV-6 infection should be considered in any child with acute meningoencephalitis.

Keywords: human herpes virus-6; meninogoencephalitis; neurological sequelae

© 1997 by Archives of Disease in Childhood


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