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a Research
Department of Human Nutrition and Centre for Advanced Food Studies, The
Royal Veterinary and Agricultural University, Frederiksberg, Denmark, b Department
of Biostatistics, University of Copenhagen, Denmark, c MRC Dunn Nutrition Centre, Cambridge
Correspondence to: Dr C Mølgaard, Research Department of Human Nutrition, The Royal Veterinary and Agricultural University, Rolighedsvej 30, DK-1958 Frederiksberg C, Copenhagen, Denmark.
Accepted 23
July 1996
Data from healthy children are needed to evaluate bone
mineralisation during childhood. Whole body bone mineral content (BMC) and bone area were examined by dual energy x ray
absorptiometry (Hologic 1000/W) in healthy girls (n=201) and boys
(n=142) aged 5-19 years. Centile curves for bone area for age, BMC for
age, bone area for height, and BMC for bone area were constructed using the LMS method. Bone mineral density calculated as BMC/bone area is not
useful in children as it is significantly influenced by bone size.
Instead, it is proposed that bone mineralisation is assessed in three
steps: height for age, bone area for height, and BMC for bone area.
These three steps correspond to three different causes of reduced bone
mass: short bones, narrow bones, and light bones.
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