Arch Dis Child 1997;76:62-64 ( January )
Graves' disease associated with exophthalmos, cerebral
ventricular dilatation and accelerated growth
Osamu Arisaka,a
Atsuto Hosaka,a
Hajime Arai,b
Sachi Fujiwara,a
Rieko Tadokoro,a
Keijiro Yabutaa
a Juntendo
University School of Medicine, Tokyo, Japan: Department of Pediatrics, b Department of Neurosurgery
Correspondence to: Dr O Arisaka,
Department of Pediatrics, Juntendo University School of Medicine,
2-1-1 Hongo, Bunkyo-ku, Tokyo 113, Japan.
Accepted 23 September 1996
A report is presented of a girl with Graves' disease, which
was diagnosed at the age of 1.7 years. The mother had no thyroid disease. The patient developed signs of hyperthyroidism shortly before
her first birthday, and the most prominent manifestations were
accelerated skeletal maturation and linear growth, and dilatation of
the brain ventricles. The latter manifestation, which has not been
reported previously, was reversible upon normalisation of thyroid
function with antithyroid treatment for three years.
Keywords:
Graves' disease;
reversible ventriculomegaly;
growth acceleration.
© 1997 by Archives of Disease in Childhood
